Central Drug Research Institute

A new facility for structural biology research has been created at CDRI. It comprises a wet laboratory housed with state-of-the-art equipments for cloning/expression and purification of proteins, a modern x-ray laboratory with P4 single crystal x-ray diffractometer system for small molecule crystallography, a MAR 345 image-plate detector on RU-300 rotating anode x-ray generator with cryo-cooling system for macromolecule crystallography, a precision camera on a FR590 x-ray generator for preliminary diffraction work and a computer graphics laboratory for molecular modelling and crystallographic computations.
The facility will be used for atomic level structure determination of proteins and small molelcules of biological and structural importance required for knowledge-based drug design through molecular modelling.