[ CAS NO. ] 9063-57-4
[ Molecular Formula ] C21H40N8O6
[ Molecular Weight ] 500.593
[ Sequence ] Thr-Lys-Pro-Arg
[ Appearance ] White Powder
[ Purity ] ≥95% or 98%
[ Function ]
2. Motility and chemotaxis;
3. Formation of reactive oxygen compounds;
4. Augmentation of tumor necrosis factor;
5. Immunmodulating activity;
6. Effect of cell cytotoxicity;
7. Nontoxicity for animals and humans;
Tuftsin is a low molecular weight tetrapeptide (Thr-Lys-Pro-Arg) secreted by the spleen, which has a wide range of biological activities and can promote phagocytosis and regulate immunity. Experiments have confirmed that it has anti-tumor effect.
Tuftsin is a physiologic tetrapeptide, which has been shown to possess immunoadjuvant properties including the stimulation of macrophage and granulocyte phagocytosis, migration, bactericidal, and tumoricidal activities. Tuftsin has also been reported to possess in vivo immunologically mediated anti-tumor potential. Some studies show that treatment of splenic effector cells with tuftsin prolongs the cytotoxic capabilities of these cells.
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