TAT-GluA2 3Y

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[ CAS NO. ] 1404188-93-7
[ Molecular Formula ] C115H185N43O29
[ Molecular Weight ] 2633.96
[ Appearance ] White Powder

About TAT-GluA2 3Y
TAT-GluA2 3Y is an interfering peptide. Its groundbreaking design allows it to penetrate cell membranes directly into neurons, maintaining synaptic inhibition and opening new avenues for the treatment of Alzheimer's disease and mitigating the side effects of anesthesia.
TAT-GluA2 3Y provides a powerful tool for understanding the molecular mechanisms of glutamatergic synaptic plasticity. By applying TAT-GluA2 3Y in cultured neurons and animal models, researchers can precisely regulate AMPA receptor endocytosis and glutamatergic synaptic function.
TAT-GluA2 3Y exhibits neuroprotective properties and may be a potential drug candidate for the treatment of neurological diseases such as Alzheimer's disease and Parkinson's disease. Furthermore, it may be used in the development of drugs to improve learning, memory, and cognitive function.
TAT-GluA2 3Y also alleviates the spatial memory deficits and synaptic inhibition caused by anesthetics such as pentobarbital (sodium pentobarbital). This may have important clinical implications for patients requiring long-term anesthetic use.