Silibinin

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[ Other Name ] Silybin; Silymarin
[ Herb Source ] Milk Thistle
[ CAS No. ] 1265089-69-7
[ Molecular Formula ] C25H22O10
[ Molecular Weight ] 482.441
[ Appearance ] White Powder

[ Function ]
1. Stabilizing Hepatocyte Membranes:
It enhances membrane stability, preventing the leakage of intracellular substances—such as transaminases—from hepatocytes into the bloodstream, thereby lowering serum transaminase levels.
2. Antioxidant and Free Radical Scavenging Effects:
Silibinin directly scavenges free radicals and enhances the activity of antioxidant enzymes within the liver, thereby mitigating the damage inflicted upon hepatocytes by oxidative stress.
3. Anti-inflammatory and Regenerative Effects:
It inhibits inflammatory signaling pathways and reduces the release of pro-inflammatory factors; concurrently, it stimulates the synthesis of RNA and proteins within hepatocytes, thereby accelerating the structural reconstruction and functional recovery of liver cells.

About Silibinin
Silibinin is an antioxidant extracted from a plant known as milk thistle.
Silibinin stabilizes hepatocyte membranes and maintains their integrity; furthermore, it promotes the restoration of hepatocyte ultrastructure, stimulates the division and growth of normal hepatocytes, and enhances their capacity for RNA and protein synthesis. It also boosts the reticuloendothelial system's ability to generate macrophages and augments macrophage activity, thereby accelerating the clearance of viruses. Concurrently, Silibinin facilitates lipid transport and exerts antioxidant effects, preventing excessive lipid peroxidation and infiltration, and thereby mitigating hepatic steatosis. Moreover, it enhances the liver's metabolic functions and strengthens its detoxification capabilities, thereby reducing the damage inflicted upon hepatocytes by toxic substances. Consequently, Silibinin serves to protect normal liver cells and promotes the recovery of damaged cell membranes.
Silibinin stabilizes hepatocyte membranes, safeguards the cellular enzymatic systems, and scavenges reactive oxygen free radicals within hepatocytes; in doing so, it enhances the liver's detoxification capacity and protects hepatocytes from the detrimental effects of prolonged exposure to toxic substances.