Pyridoxal 5'-phosphate Monohydrate

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[ CAS No. ] 41468-25-1
[ Molecular Formula ] C8H12NO7P
[ Molecular Weight ] 265.1571
[ Appearance ] Pale Yellow Powder
[ Purity ] ≥98.5%

[ Function ]
1. Amino Acid Metabolism:
It participates in numerous amino acid metabolic reactions and serves as a cofactor for these processes.
2. Neurotransmitter Synthesis:
It plays a pivotal role in the synthesis of serotonin (which regulates mood and sleep) and gamma-aminobutyric acid (GABA).
3. Hemoglobin Synthesis:
It promotes the synthesis of porphyrin precursors and facilitates the absorption and utilization of iron, thereby influencing hematopoietic function.
4. Detoxification and Immunity:
It assists the liver in the metabolism of drugs and toxins, while also regulating the function of immune cells.
5. Antioxidant Defense:
It neutralizes free radicals and mitigates oxidative damage to neurons.
6. Anti-inflammatory Effects:
It inhibits microglia from releasing pro-inflammatory factors—such as IL-6 and TNF-α—thereby blocking the cascade of neuroinflammation.
7. Promotion of BDNF Production:
It enhances the expression of Brain-Derived Neurotrophic Factor (BDNF), thereby supporting neuronal survival and synaptic remodeling.

[ Application ]
1. Pharmaceuticals: 
Used for the treatment of Vitamin B₆ deficiency, pregnancy-related vomiting, leukopenia, and as an adjuvant therapy for neurological disorders.
2. Food: 
Added as a nutritional fortifier to foods such as infant formulas and cereal products.
3. Animal Feed: 
Added to animal feed to enhance growth performance and immune function; commonly used in poultry and swine farming.

About Pyridoxal 5'-phosphate Monohydrate
Pyridoxal 5'-phosphate Monohydrate is the active form of Vitamin B6 within the body. Intracellularly, it serves as the most critical coenzymatic variant produced during the phosphorylation of Vitamin B6, and it is interconvertible with other variants. It acts as a multifunctional coenzyme, participating extensively in a wide array of biochemical processes—playing a particularly pivotal role in amino acid metabolism. As an essential cofactor for numerous enzymes, it is involved in key biological processes such as the synthesis of the neurotransmitters dopamine and serotonin, general amino acid metabolism, and hemoglobin production.
As a coenzyme for various amino acid metabolic reactions, Pyridoxal 5'-phosphate Monohydrate plays a significant role in facilitating processes such as amino acid transamination and decarboxylation. It promotes the decarboxylation of glutamate to produce gamma-aminobutyric acid (GABA), an important inhibitory neurotransmitter. Furthermore, Pyridoxal 5'-phosphate Monohydrate serves as a key coenzyme in the metabolism of citrulline and ornithine.
Pyridoxal 5'-phosphate Monohydrate participates in a multitude of reactions within human metabolism. It functions as a coenzyme for various enzymes, facilitating their catalytic activity. It is involved in amino acid metabolic pathways and is critical for protein synthesis. Pyridoxal 5'-phosphate Monohydrate also plays a positive role in lipid metabolic pathways. It holds significant importance in the metabolic processes of carbohydrates, lipids, and amino acids.
In the pharmaceutical sector, Pyridoxal 5'-phosphate Monohydrate is utilized in the formulation of various medications. It serves as a key active ingredient in drugs designed to treat Vitamin B6 deficiency. Additionally, it acts as an adjuvant in the treatment of certain neurological disorders. Within the nutritional supplement industry, Pyridoxal 5'-phosphate Monohydrate enjoys widespread application; it enhances both the nutritional value and efficacy of dietary supplements. In the food industry, it is employed as a nutritional fortifier added to various food products. When incorporated into baked goods, it boosts the nutritional profile of the final product. Similarly, adding Pyridoxal 5'-phosphate Monohydrate to beverages can enhance their health-promoting properties.