Palmitoylethanolamide

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[ Synonyms ] N-(2-Hydroxyethyl)hexadecanamide; PEA; Palmidrol
[ CAS No. ] 544-31-0
[ Molecular Formula ] C18H37NO2
[ Molecular Weight ] 299.49
[ Appearance ] White Powder
[ Purity ] 99%

[ Function ]
1. Acts as a nuclear receptor transcription factor;
2. Reduces degranulation and infiltration of immune cells;
3. Effective for neuropathic pain, sciatica, osteoarthritis, and other chronic pain conditions;
4. Reduces neuroinflammation and pro-inflammatory cytokines;
5. Helps regulate mast cell activation;

About Palmitoylethanolamide
Palmitoylethanolamide is a naturally occurring fatty acid amide that exerts its biological effects primarily by activating Peroxisome Proliferator-Activated Receptor-alpha (PPAR-α). It possesses broad anti-inflammatory and antimicrobial activities, as well as functions such as regulating aqueous humor outflow channels, lowering intraocular pressure, and providing neuroprotection; consequently, it is utilized in research related to epilepsy and glaucoma.
Palmitoylethanolamide has demonstrated anti-inflammatory, anti-nociceptive, neuroprotective, and anticonvulsant properties. It has been investigated in various human clinical trials for the management of diverse pain states, as well as for inflammatory and pain syndromes.
Palmitoylethanolamide is widely utilized in health supplements and cosmetic products. Given its unique influence on factors governing cellular function, Palmitoylethanolamide holds promising prospects for a wide range of clinical applications.