Mitoquinone Mesylate (MitoQ)
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[ Other Name ] Mitoquinone Mesylate; MitoQ
[ CAS NO. ] 845959-50-4
[ Molecular Formula ] C38H47O7PS
[ Molecular Weight ] 678.82
[ Appearance ] Orange Powder
[ Purity ] ≥98% (HPLC)
[ Function ]
1. Cardioprotection;
2. Anti-inflammatory;
3. Immunomodulation;
4. Anti-fibrotic;
5. Anti-tumor;
[ Application ]
It is used in basic research concerning cellular oxidative stress, mitochondrial function, and neuroprotection.
About Mitoquinone Mesylate (MitoQ)
Mitoquinone Mesylate is a mitochondria-targeted antioxidant appearing as an orange solid that is readily soluble in DMSO (dimethyl sulfoxide); its primary function is to protect cells from damage caused by harmful substances such as reactive oxygen species (ROS) by targeting mitochondria and reducing oxidative damage. Due to its potent immunosuppressive effects, Mitoquinone Mesylate has been approved by the FDA for the treatment of patients with worsening relapsing-remitting multiple sclerosis (RRMS) or secondary progressive multiple sclerosis (SPMS), with the aim of reducing relapse frequency and delaying the progression of disability.
As a mitochondria-targeted antioxidant, mitoquinone mesylate can reduce axonal inflammation and oxidative stress and protect neurons, thereby offering therapeutic potential for neurological disorders such as Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis.
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