Magainin 1

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[ Other Name ] Magainin I Peptide
[ Sequence ] Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser
[ CAS NO. ] 108433-99-4
[ Molecular Formula ] C112H177N29O28S
[ Molecular Weight ] 2409.88
[ Appearance ] White Powder
[ Purity ] ≥98%
About Magainin 1
Magainin 1 (Magainin I) is an antimicrobial and amphiphilic peptide isolated from the skin of Xenopus laevis. Magainin 1 exhibits antibiotic activity against a wide range of Gram-negative and Gram-positive bacteria.
Magainin 1 exhibits antibiotic activity against a wide range of Gram-negative and Gram-positive bacteria, meaning it can inhibit or kill these bacteria, thereby protecting the body from infection. This broad spectrum of antimicrobial activity makes Magainin 1 a potential drug candidate for the treatment of bacterial infections.
Magainin 1 also has other important biological functions. It exerts its antimicrobial effect by disrupting the integrity of bacterial cell membranes. This mechanism differs from that of other traditional antibiotics, and therefore, Magainin 1 may remain effective against some bacteria that have become resistant to traditional antibiotics.
Furthermore, Magainin 1 can serve as a model molecule for studying the mechanism of action and structure-activity relationship of antimicrobial peptides. By altering its amino acid sequence or structure, its antimicrobial activity can be further optimized, leading to the development of more effective antimicrobial drugs.
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