Lapatinib

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[ CAS NO. ] 231277-92-2
[ Molecular Formula ] C29H26ClFN4O4S
[ Molecular Weight ] 581.06
[ Appearance ] White Powder

[ Function ]
Suitable for second-line treatment of advanced or metastatic breast cancer.

About Lapatinib
Lapatinib is a tyrosine kinase inhibitor that controls tumor cell growth and division by interfering with signaling pathways and reducing the spread and metastasis of cancer cells.
The mechanism of action of lapatinib is to inhibit the signaling of EGFR/HER2 double mutants within cancer cells, thereby inhibiting the growth and division of cancer cells. HER2-positive breast cancer is a type of cancer that is highly dependent on the HER2 signaling pathway. Lapatinib can bind to kinases in the HER2 signaling pathway, thereby blocking their effects, thus inhibiting the HER2 signaling pathway and reducing the progression of HER2-positive advanced or metastatic breast cancer.
Lapatinib is primarily used in the treatment of breast cancer. As a monotherapy, lapatinib is used to treat HER2-positive advanced or metastatic breast cancer and may be the preferred drug before chemotherapy. When used in combination with chemotherapy drugs, lapatinib is used to treat HER2-positive advanced or metastatic breast cancer, improving efficacy. In addition, lapatinib can also be used to prevent recurrence of HER2-positive breast cancer.