Ketoconazole

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[ CAS NO. ] 65277-42-1
[ Molecular Formula ] C26H28Cl2N4O4
[ Molecular Weight ] 531.43
[ Appearance ]  White Powder
[ Purity ] 99%

[ Function ]
1. Antifungal Mechanism:
Inhibits the synthesis of ergosterol in fungal cell membranes and disrupts membrane structure, thereby killing or inhibiting the growth of pathogenic fungi such as malassezia.
2. Anti-inflammatory and Regulatory Effects:
Alleviates scalp inflammation and redness; regulates sebaceous gland function to reduce excessive sebum secretion and improve an oily scalp environment.
3. Dandruff and Itch Relief:
Significantly reduces dandruff shedding and relieves intense itching caused by fungal infections.
4. Oil Control and Cleansing:
Reduces scalp oil secretion, keeps hair follicles clear, and helps prevent fungal recurrence.

About Ketoconazole
Ketoconazole is a broad-spectrum imidazole antifungal drug. It inhibits fungal growth by blocking the biosynthesis of ergosterol—an essential component for maintaining fungal cell structure—through the inhibition of fungal cytochrome P-450 enzyme activity, thereby disrupting the integrity of the fungal cell membrane. It also alters the composition of other lipids within the cell membrane, ultimately killing the fungus.
Ketoconazole is essentially a medicinal lotion containing antifungal agents; it is primarily used to treat stubborn dandruff, scalp itching, and seborrheic dermatitis caused by malassezia fungi.