JMV 449

Buy JMV 449 Powder at Wholesale Price. Direct Factory Supply. JMV 449 COA, Price, For Sale with High Quality and Lowest Price.
Purchase JMV 449 Peptide From Manufacturer/Supplier - Bolise. Get Quote Bulk Inquiry.

[ CAS No. ] 139026-66-7
[ Molecular Formula ] C38H66N8O7
[ Molecular Weight ] 746.98
[ Appearance ] White Powder
[ Purity ] ≥95% by HPLC

About JMV 449
JMV 449 is a highly specific neurotensin receptor agonist that holds a significant position in biomedical research and drug development. This peptide is noted for its potent binding affinity to neurotensin receptors and plays a key role in processes such as the regulation of body temperature, pain perception, and potentially the functioning of the digestive system.
In the field of neuroscience, JMV 449 is used to investigate the role of the neurotensin system in regulating body temperature, mood, and pain processing. Its high selectivity makes it an ideal tool for studying specific neurotensin receptor subtypes.
The use of JMV 449 contributes to an understanding of the potential value of neurotensin receptor agonists in the treatment of pain, fever, and other related conditions, offering insights for the development of novel therapeutic agents.
Research has also explored the interaction between JMV 449 and pancreatic β-cells, as well as its synergistic effects with incretin mimetics such as GIP and GLP-1—suggesting potential applications in blood glucose regulation and the treatment of diabetes.

Frequently Asked Questions
Q1: What is JMV 449 used for?
JMV 449 is primarily used in neuroscience and pharmacological research to study neurotensin receptor activation, GPCR signaling, pain modulation, and thermoregulation.

Q2: Is JMV 449 a peptide?
Yes. It is a synthetic pseudopeptide and a modified analogue of Neurotensin (8–13).

Q3: Is JMV 449 a neurotensin receptor agonist?
Yes. It acts as a potent agonist of neurotensin receptors.

Q4: Is JMV 449 metabolically stable?
Compared with native neurotensin, its modified peptide bond provides increased resistance to enzymatic degradation.