Isoquercetin
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[ Other Name ] Quercetin 3-glucoside; Hirsutrin; Isoquercetin; Isoquercitroside
[ Source ] Apocynum venetum L.
[ CAS NO. ] 482-35-9
[ Molecular Formula ] C21H20O12
[ Molecular Weight ] 464.379
[ Appearance ] Light Yellow to Yellow Powder
[ Purity ] 98%, HPLC
[ Function ]
1. Respiratory System Support:
Isoquercitrin inhibits the release of certain inflammatory factors in the body, helping to alleviate airway hyper-responsiveness and thereby acting to clear phlegm, suppress coughs, and relieve asthma.
2. Antioxidant Properties and Delaying Cellular Damage:
As an antioxidant, isoquercitrin helps the body eliminate harmful free radicals and reduces oxidative stress-induced cellular damage; this plays a fundamental, positive role in delaying aging and preventing chronic diseases.
3. Anti-inflammatory Effects:
It can modulate the body's inflammatory signaling pathways, potentially helping to alleviate chronic inflammation. This shows promise in areas such as cardiovascular protection and metabolic improvement.
4. Immune and Antiviral Support:
It helps maintain immune balance by regulating the activity of immune cells.
About Isoquercetin
Isoquercitrin is found in the roots, bark, and leaves of various plants—such as willow bark and ginkgo leaves—and is one of the active ingredients responsible for the efficacy of many traditional herbal medicines.
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway. Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies.
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