Hydroxypropyl Methylcellulose (HPMC)

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[ CAS No. ] 9004-65-3
[ Appearance ] White Powder
[ Purity ] ≥99%

[ Function ]
1. Used as a coating for tablets and capsules to enhance appearance, mask unpleasant odors, and control the rate of drug release;
2. Delays drug dissolution by forming a gel layer, thereby achieving sustained and controlled release—as seen in sustained-release tablets and controlled-release capsules;
3. Enhances powder binding strength and improves molding stability during tablet manufacturing;
4. Acts as a lubricant to alleviate dry eye symptoms, simulating the function of natural tears;
5. Incorporated into ointments and gels to enhance stability and spreadability;
6. Retains moisture in baked goods, thereby extending shelf life;
7. Used in dairy products, sauces, and similar items to adjust texture and mouthfeel, while preventing separation or clumping;

[ Application ]
1. Pharmaceutical Field:
Used for tablet coatings, matrix materials for sustained-release formulations, thickening agents for eye drops, and similar applications.
2. Food Industry:
Used as an emulsifier and thickening agent; certain grades can serve as a substitute for animal gelatin in foods such as jellies, candies, sauces, and more.

About Hydroxypropyl Methylcellulose (HPMC)
Hydroxypropyl Methylcellulose (HPMC) is a non-ionic cellulose derivative that serves primarily as a thickening agent, stabilizer, film-forming agent, and water-retention agent. Widely utilized in fields such as construction materials, pharmaceuticals, food, and daily chemical products, it is characterized by its safety, non-toxicity, and biodegradability.
Hydroxypropyl Methylcellulose (HPMC) is a commonly used pharmaceutical excipient, typically employed in solid dosage forms—such as tablets and capsules—as a binder, disintegrant, and film-coating material.
Hydroxypropyl Methylcellulose (HPMC) can be used for the film coating of tablets and capsules to enhance the drug's appearance, palatability, and stability. Furthermore, it acts as a barrier against external environmental factors, thereby extending the drug's shelf life.
In the food industry, Hydroxypropyl Methylcellulose (HPMC) is used to improve food texture and extend shelf life; in cosmetics, it helps to enhance skin feel and product stability. Additionally, it functions as a protective colloid, effectively reducing the sedimentation of solid particles within liquid systems.