Hirudin

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[ CAS NO. ] 8001-27-2
[ Molecular Formula ] C287H440N80O113S7
[ Molecular Weight ] Approximately 7.0kDa, a single non-glycosylated polypeptide chain containing 63 amino acid residues.
[ Appearance ] White Powder
[ Purity ] >98.0%

[ Function ]
1. Hirudin is a thrombin inhibitor with blood anticoagulant property. 
2. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. 
3. Hirudin also affects diabetic complications, cerebral hemorrhage, and others.

About Hirudin
Hirudin is a naturally occurring anticoagulant, or blood thinner, that is derived from the saliva of medicinal leeches. It was one of the first anticoagulants to be discovered and has been used for medical purposes for centuries.
Hirudin works by inhibiting thrombin, which is an enzyme involved in the clotting process. By blocking thrombin, hirudin prevents the formation of blood clots. This can be beneficial in certain medical conditions where excessive clotting can occur, such as deep vein thrombosis, pulmonary embolism, or certain cardiovascular disorders.
In the past, hirudin was primarily obtained by extracting it from the salivary glands of leeches. However, advances in biotechnology have allowed for the production of synthetic or recombinant hirudin, which is now more commonly used in medical settings. Synthetic hirudin has the advantage of being more readily available and standardized in its potency.
Hirudin has been used in various medical procedures, including preventing blood clotting during surgeries, particularly in cases where heparin, another commonly used anticoagulant, is contraindicated. It has also been used in the treatment of certain cardiovascular conditions, such as acute coronary syndromes.