Gonadorelin

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[ Cas NO. ] 33515-09-2
[ Molecular Formula ] C55H75N17O13
[ Molecular Weight ] 1182.311
[ Appearance ] White Crystal Powder
[ Purity ] 98%

[ Function ]
1. For the diagnosis of hypothalamic-pituitary-gonadal dysfunction.
2. Treatment of infertility caused by amenorrhea, insufficient secretion of gonadotropin and multi-follicular ovary.
3. Gonadorelin or its analogs buserelin, goserelin, leuprolide, nafarelin and triptorelin can also be used for contraception, cryptorchidism, malignant tumors (especially prostate cancer) , delayed and early puberty.
4. It can also be used for endometriosis.
5. It is used for ovulation induction to treat infertility and primary ovarian insufficiency caused by hypothalamic amenorrhea, especially for patients who are ineffective for clomiphene.
6. It is also used for cryptorchidism in children, androgen excess, and pituitary tumors.

About Gonadorelin
Gonadorelin is a synthetic gonadotropin-releasing hormone, which belongs to peptide compounds and is a decapeptide. This product can stimulate the pituitary gland to synthesize and release gonadotropins (FSH and LH), and gonadotropins stimulate the gonads to release sex hormones. Hypothalamic gonadotropin-releasing hormone secretion is regulated by several factors, including circulating sex hormones. When used as a single agent, it can increase circulating sex hormones; continuous use can cause downregulation of gonadotropin-releasing hormone receptors in the pituitary gland, thereby reducing the secretion of sex hormones.
Gonadorelin is mainly used in the differential diagnosis of male or female fertility disorders due to hypothalamic or pituitary hypofunction, gonadal atrophic hypogonadism, galactorrhea amenorrhea, primary and secondary amenorrhea, menopause, and precocious menopause , pituitary tumors, organ damage to the pituitary gland, and de facto hypothalamic dysfunction.
Gonadorelin can be used in the diagnosis of hyposexuality caused by hypothalamic or pituitary insufficiency, and can also be used in the diagnosis or treatment of related infertility conditions.