Genistein

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[ CAS NO. ] 446-72-0
[ Molecular Formula ] C15H10O5
[ Molecular Weight ] 270.24
[ Apparence ]  Light Yellow Powder

[ Function ]
1. Antioxidant
Scavenges free radicals, activates the body's endogenous antioxidant enzyme systems, and mitigates oxidative damage to cells.
2. Anti-inflammatory
Inhibits inflammatory pathways such as NF-κB and reduces the production of pro-inflammatory cytokines, helping to alleviate chronic low-grade inflammation.
3. Bidirectional estrogen regulation
Structurally similar to estrogen; exerts weak estrogenic effects when endogenous estrogen levels are low (alleviating hot flashes, night sweats, and headaches) and acts as a competitive inhibitor when estrogen levels are high (reducing excessive stimulation).
4. Bone protection
Promotes osteoblast activity and inhibits osteoclasts; some studies indicate it can reduce postmenopausal bone loss and help maintain bone density.
5. Cardiovascular health maintenance
Improves vascular endothelial function and regulates blood lipids, helping to lower the risk of atherosclerosis.
6. Inhibition of angiogenesis and cell proliferation
Can inhibit tumor angiogenesis as well as the activity of certain tyrosine kinases and topoisomerase II.
7. Relief of menopausal symptoms
Alleviates menopausal symptoms and balances estrogen levels.
8. Sedative and calming effects
Helps alleviate symptoms of poor sleep, providing a sedative and calming effect.

About Genistein
Genistein is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, and other legumes. 
Genistein can combine with estrogen receptor and have weak estrogen effect. So it is also called phytoestrogen. It is antagonistic to estrogen. It has protective effect or hormone related diseases. It can improve and prevent climacteric syndrome and osteoporosis. 
The core functions of genistein include antioxidant and anti-inflammatory effects, as well as the bidirectional regulation of estrogen; it is commonly used to alleviate menopausal discomfort and support bone and cardiovascular health, while its anti-tumor potential remains under investigation.
Genistein can serve as food supplement to be widely used in various healthy food for the middle-aged and old people.