Examorelin
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[ Other Name ] Examorelin; Hexarelin
[ CAS NO.] 140703-51-1
[ Molecular Formula ] C47H58N12O6
[ Molecular Weight ] 887.059
[ Appearance ] White Powder
[ Purity (HPLC) ] 98%
[ Function ]
1. Cardioprotective effects:
Studies indicate that Hexarelin improves myocardial function, inhibits cardiomyocyte apoptosis, attenuates ischemia/reperfusion injury, and ameliorates atherosclerotic lesions.
2. Neuroprotection and anti-epileptic activity:
Hexarelin demonstrates dose-dependent anti-epileptic effects, reducing neuronal damage in the hippocampus and improving memory impairment.
3. Renal protection:
Hexarelin significantly attenuates oxidative stress injury caused by renal ischemia/reperfusion and enhances total antioxidant capacity.
4. Metabolic regulation:
This substance helps reduce visceral fat and improve lipid metabolism, holding potential value for research into endocrine and metabolic diseases.
About Examorelin
Examorelin is a synthetic hexapeptide growth hormone secretagogue. It stimulates the release of growth hormone (GH) by activating the growth hormone secretagogue receptor (GHS-R) and the scavenger receptor CD36, while also exhibiting biological activities—such as cardioprotection, neuroprotection, and anti-atherosclerotic effects—that are independent of growth hormone.
As a potent GH-releasing peptide, Examorelin significantly elevates serum levels of insulin-like growth factor-1 (IGF-1), promoting muscle growth and improving lipid metabolism. Unlike the similar compound GHRP-6, Hexarelin does not cause a significant increase in appetite.
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