Dihydroergotoxine Mesylate

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[ Other Name ] Ergoloid; Ergoloid Mesylate; Hydergine
[ CAS NO. ] 8067-24-1
[ Molecular Weight ] 423.53
[ Appearance ] White Powder
[ Purity (HPLC) ] ≥98.0%

[ Function ]
1. Vasodilation: Blocks α-receptors, reduces cerebrovascular resistance, and increases cerebral blood flow and oxygen utilization.
2. Neurotransmitter modulation: Acts as a partial agonist/antagonist at dopamine and serotonin receptors, improving synaptic transmission.
3. Metabolic improvement: Promotes aerobic glucose metabolism in brain cells, shortens cerebral circulation time, and improves EEG abnormalities.

About Dihydroergotoxine Mesylate
Dihydroergotoxine mesylate is a mixture of semi-synthetic ergot alkaloids that acts primarily as an alpha-adrenergic receptor blocker to improve cerebral metabolism and blood circulation; it has been widely used in the treatment of cognitive impairment in the elderly and the sequelae of cerebrovascular disease. It is a semi-synthetic ergot alkaloid compound mainly used in pharmaceutical applications, particularly in research and treatment related to cognitive function, cerebral circulation, and vascular regulation.