[ CAS NO. ] 65928-58-7
[ Molecular Formula ] C20H25NO2
[ Molecular Weight ] 311.425 g/mol
[ Density ] 1.2 g/cm3
[ Boiling point ] 549 °C (1,020 °F)
[ Melting point] 212.2-214.5℃
[ Appearance ] White to almost white crystalline powder
[ Main Function ] Indicated for use as the treatment of endometriosis alone and as a contraceptive in combination with ethinylestradiol.
COA of Dienogest
Specific rotation: -274.58
Loss on drying: 0.08%
Residue on ignition: 0.05%
Residual solvents(Methanol): ≤3000ppm
Residual solvents(Dichloroethane): ≤ 600ppm
Individual impurity: 0.07%
Total related substances: ≤1.5%
Dienogest is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive.
Dienogest is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. Dienogest has antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive.
It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. It is a non-ethinylated progestin which is structurally related to testosterone.
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