Dienogest

Dienogest

[ CAS NO. ]  65928-58-7
[ Molecular Formula ]  C20H25NO2
[ Molecular Weight ]  311.425 g/mol
[ Density ]  1.2 g/cm3
[ Boiling point ]  549 °C (1,020 °F)
[ Melting point]  212.2-214.5℃
[ Appearance ]  White to almost white crystalline powder
[ Main Function ]  Indicated for use as the treatment of endometriosis alone and as a contraceptive in combination with ethinylestradiol. 
COA of Dienogest
Specific rotation:  -274.58
Loss on drying:  0.08%
Residue on ignition:  0.05%
Residual solvents(Methanol):  ≤3000ppm
Residual solvents(Dichloroethane):   ≤ 600ppm
Individual impurity:  0.07%
Total related substances:  ≤1.5%
Assay(HPLC):  99.94%
About Dienogest
Dienogest is an orally-active, semisynthetic, fourth generation, nonethinylated progestogen with antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive. 
Dienogest is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis. Dienogest has antiproliferative, antiandrogenic, anti-inflammatory and antiangiogenic activities that is used in hormone therapy and as a female contraceptive. 
It is available for use as an oral contraceptive in combination with ethinylestradiol. It has antiandrogenic activity and as a result can improve androgenic symptoms. It is a non-ethinylated progestin which is structurally related to testosterone. 

 

 

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