[ CAS NO. ] 13739-02-1  
[ Molecular Formula ] C19H12O8
[ Molecular weight ] 368.297
[ Appearance ] Fine crystalline yellowish powder
[ Main Function ]
1. Diacerein is the most important  depressant used to treat  osteoarthritis;
2. The experimental evidence shows that it can induce the generation of gristle;
3. For osteoarthritis, Diacerein has an effect of delaying the disease process;
4. Diacerein also has the effect of alleviatingpain, anti-inflammatory, defervescence.
[ Application ] 
Clinical trials have shown tha diacerein is highly effective in relieving the symptoms of osteoarthritis. Moreover, results from studies conducted in vitro, in animals and in humans indicate that it may be able to modify the course of the disease. Diacerein has a unique mode of action, namely the inhibition of IL,which distinguishes it from other drugs indicated for the treatment of osteoarthritis.In many in vitro models, therapeutic levels of diacerein and rhein, its active metabolite, have been shown to inhibit the synthesis and activity of IL1, as well as to stimulate anabolic processes. 
COA of Diacerein
Identification: IR,HPLC
Related substance(HPLC)    
Single impurities:  0.32%
Total impurities: 0.58%
Chromium complies: ≤50.0 ppm
Color of solution(440nm): 0.19
Mesh size/sieve analysis complies:  100%pass 80 mesh
Loss on drying:  ≤2.0%  
Sulphated ash:  ≤1%
Heavy metals:  <20ppm  
Total Plate Count:  <1000cfu/g
Yeast & Mold: <100cfu/g
E.Coli:  Negative
S. Aureus:  Negative    
Salmonella:  Negative
About Diacerein
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
[ Storage ]  Store in sealed containers at cool & dry place.
Protect from light, moisture and pest infestation. 
[ Shelf life ] 2 years when properly stored



Please feel free to contact usfor: the product Quotation (the product price),COA (Certificate of Analysis),New Sales Promotion,New Products,And any other assistance.

For more information of product, please send the email to bkherb@globals-globals.com

Bolise Co., Limited.

Bolise Co., Limited.After send online enquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email.This form is unable to receive your inquiry from aol, hotmail, gmail or others but company email address.

TEL: +86 592 536 5868
WHATSAPP: +86 189 6516 2351