Dermatan Sulfate

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[ CAS NO. ] 24967-94-0
[ Molecular Formula ] C14H21NO15S
[ Molecular Weight ] 475.37
[ Appearance ] White Powder
 [ Purity ] ≥95% (HPLC)

[ Function ]
1. Anticoagulant effect: Reduces the risk of thrombosis by inhibiting the activity of coagulation factors, but the effect is weaker than heparin;
2. Cell regulation: Participates in cell proliferation, migration and inflammatory response, affects wound healing and immune regulation;
3. Structural support: As a component of the extracellular matrix, it maintains tissue elasticity and moisture, and delays skin aging;

[ Application ]
1. Pharmaceuticals:
Anti-thrombotic therapy: Auxiliary prevention of postoperative thrombosis, needs to be used in combination with other anticoagulants.
Wound repair: Promote the healing of chronic ulcers or burns, often applied topically in the form of gel or dressing.
Ophthalmology: As a viscoelastic agent to protect the corneal endothelium.
2. Skin care products:
Moisturizing and repairing: Strengthen the skin barrier, improve dryness and sensitivity problems.
Anti-aging: Stimulate collagen synthesis, reduce wrinkles and sagging.

About Dermatan Sulfate
Dermatan sulfate is a naturally occurring glycosaminoglycan widely distributed in connective tissues such as skin, blood vessels, and cartilage.
Dermatan sulfate is composed of repeated disaccharide units, containing iduronic acid and N-acetylgalactosamine, and its biological activity is enhanced by sulfate modification.
It is mainly found in the dermis of the skin, blood vessel walls, heart valves, and cartilage, and maintains tissue structure and function together with collagen, elastin, etc.
It plays an important role in the fields of medicine and skin care through mechanisms such as anticoagulant activity, regulating cell function, and promoting tissue repair.