Daptomycin

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[ CAS No. ] 103060-53-3
[ Molecular Formula ] C72H101N17O26
[ Molecular Weight ] 1619.708
[ Density ] 1.45 g/cm3
[ Index of Refraction ] 1.638
[ Flash Point ] 1210.7 °C
[ Boiling Point ] 2078.2 °C at 760 mmHg
[ Appearance ] Light Yellow Powder

[ Function ]
By binding to the bacterial cell membrane and forming transmembrane channels, it causes leakage of cellular contents, thereby killing the bacteria.

[ Uses ]
A pharmaceutical intermediate used in the treatment of complicated skin and skin structure infections caused by certain Gram-positive susceptible bacterial strains.

About Daptomycin
Daptomycin is a novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. It is a naturally-occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action means that it may be useful in treating infections caused by multi-resistant bacteria.
The primary mechanism of action of daptomycin is to kill bacteria by disrupting their cell membranes. It interacts with phosphatidylglycerol in the bacterial cell membrane, causing structural changes that compromise the integrity of the membrane. This prevents the bacteria from maintaining normal physiological functions, ultimately leading to bacterial death.