Crisaborole

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[ CAS NO. ] 906673-24-3
[ Molecular Formula ] C14H10BNO3
[ Molecular Weight ] 251.05
[ Appearance ] White Powder 
[ Purity ] ≥98% (HPLC)

[ Function ]
1. Anti-inflammatory effect:
By inhibiting PDE-4 enzyme activity, it reduces the levels of pro-inflammatory cytokines (such as TNF-α and IL-17), thereby alleviating skin inflammatory reactions and relieving acute eczema flare-ups.
2. Anti-itch and repair:
It reduces the release of neurogenic inflammatory mediators, relieves itching and discomfort, and at the same time promotes skin barrier repair, reducing allergic reactions caused by external stimuli.

About Crisaborole
Crisaborole is a chemical agent primarily used as a disinfectant and bactericide. It can be used to disinfect and kill many different types of bacteria and viruses, including some common pathogens. It can also be used in the treatment of some skin infections and diseases, such as acne and athlete's foot.
Crisaborole has a broad-spectrum bactericidal effect, effectively inhibiting and killing various bacteria, viruses, fungi, and parasites, and effectively preventing the spread of infectious diseases. Crisaborole can also be used to prevent and treat skin infections, for wound disinfection and cleaning, and has anti-inflammatory effects.
Its mechanism of action is through inhibiting the activity of phosphodiesterase-4 (PDE-4) enzyme in the skin, reducing the release of inflammatory factors, thereby relieving symptoms such as redness and itching caused by eczema. As a non-steroidal drug, it is suitable for patients who require long-term symptom control or have concerns about steroid treatment.