Cisplatin

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[ CAS NO. ] 15663-27-1
[ Molecular Formula ] [Pt(NH3)2Cl2]
[ Molecular Weight ] 300.05
[ Appearance ] Orange-yellow Crystalline Powder

[ Function ]
1. DNA cross-linking: After entering the cell, cisplatin is hydrolyzed into active substances that bind to guanine bases on the DNA strand, forming intra- or inter-strand cross-links, thus hindering DNA replication and transcription.
2. Induction of apoptosis: DNA damage triggers repair mechanisms in cancer cells; if repair fails, programmed cell death (apoptosis) is initiated.
3. Inhibition of cell division: It interferes with mitosis, preventing cancer cell proliferation.

About Cisplatin
Cisplatin is a broad-spectrum anti-cancer drug belonging to the platinum-based chemotherapy class. It inhibits tumor growth by disrupting the DNA replication function of cancer cells and is widely used in the treatment of various solid tumors, including testicular cancer, ovarian cancer, bladder cancer, and lung cancer.