[ CAS No. ] 64485-93-4
[ Molecular Formula ] C16H17N5O7S2
[ Molecular Weight ] 455.46
[ Appearance ] White Powder
[ Medical uses ]
Lower respiratory tract infections - e.g. pneumonia;
Genitourinary system infections - urinary tract infections ;
Intra-abdominal infections - e.g. peritonitis
Bone and joint infections
Cefotaxime is a third-generation cephalosporin and is a broad-spectrum antibiotic. The effect on Gram-negative bacilli is significantly better than that of the first and second-generation cephalosporins, especially against influenza bacillus,Escherichia coli, Enterobacter, Citrobacter, Serratia, Klebsiella and β. - The action of lactamase-resistant Escherichia coli is stronger than that of cefoperazone, and the effect of Haemophilus producing penicillinase is the strongest.
Cefotaxime treatment of patients with hematological malignancies has the best clinical response and long duration of bactericidal action, but the bactericidal effect on Pseudomonas aeruginosa and Enterobacter cloacae is poor.
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