Calcium D-Glucarate

Calcium D-Glucarate

[ Synonyms ]  Calcium Gluconate
[ CAS NO. ]   299-28-5 
[ Molecular Formula ] C12H22CaO14(anhydrous); C12H22CaO14· H2O (monohydrate) or C12H22CaO14
[ Formula Weight ]  430.372 
[ Appearance ]  White crystal.or granular powder
[ Purity ]  99.0~102.0%
COA of Calcium D-Glucarate
PH    6.0~8.0: ≤0.5%
Loss on drying:  ≤10ppm
Heavy metals:  ≤500ppm
Chloride:  ≤500ppm
Sulphate:  ≤2ppm
About Calcium D-Glucarate
Calcium D-Glucarate is a relatively common nutrient found in many fruits and vegetables. Calcium-D-Glucarate is a β-glucuronidase inhibitor that promotes the excretion of any molecule in a specific detoxification pathway. It has shown efficacy at very high (impractical) oral doses in reducing cancer induced by these compounds, but may also reduce all steroid hormones as well.
Calcium D-Glucarate is the calcium salt of D-glucaric acid, a substance produced naturally in small amounts by mammals, including humans. Glucaric acid is also found in many fruits and vegetables with the highest concentrations to be found in oranges, apples, grapefruit, and cruciferous vegetables. Calcium D-Glucarate has been shown to inhibit beta-glucuronidase, an enzyme produced by colonic microflora and involved in Phase II liver detoxification. Elevated beta-glucuronidase activity is associated with an increased risk for various cancers, particularly hormone-dependent cancers such as breast, prostate, and colon cancers. Other potential clinical applications of D-Glucarate include regulation of estrogen metabolism and as a lipid-lowering agent.
Calcium D-Glucarate is the gluconate salt of calcium. An element or mineral necessary for normal nerve, muscle, and cardiac function, calcium as the gluconate salt helps to maintain calcium balance and prevent bone loss when taken orally. Calcium D-Glucarate may also be chemopreventive for colon and other cancers. 



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