CAD031
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[ Other Name ] CAD-031; CAD-31
[ CAS No. ] 2071209-49-7
[ Molecular Formula ] C18H14F6N2O2
[ Molecular Weight ] 404.31
[ Purity ] >98%
[ Appearance ] Light Yellow to Yellow Solid Powder
[ Solubility ] Soluble in DMSO
[ Function ]
1. It helps improve mitochondrial function and energy production in the brain's cells.
2. It protects nerve cells from various toxicities associated with the aging brain.
3. It can effectively enhance memory and improve dendritic structure.
4. It may promote the birth of new neurons.
About CAD031
CAD031, a J147 derivative targeting Alzheimer's disease (AD), exhibits neuroprotective and memory-enhancing properties. CAD031 is capable of crossing the blood-brain barrier; it activates AMPK and inhibits ACC1, thereby increasing acetyl-CoA levels, improving mitochondrial function, and reducing free fatty acid synthesis. Possessing neuroprotective, neurogenesis-promoting, and memory-enhancing activities, CAD031 is applicable to research on Alzheimer's disease and age-related neurodegenerative disorders. Compared to J147, CAD031 demonstrates superior activity in assays utilizing human neural stem cells.
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