BAM15

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[ CAS NO. ] 210302-17-3
[ Molecular Formula ] C16H10F2N6O
[ Molecular Weight ] 340.294
[ Appearance ] White Powder
[ Purity ] 98%

[ Function ]
1. Fat reduction and improved metabolism:
Through mitochondrial uncoupling, it significantly reduces body fat (animal model body fat reduction> 20%), while reducing blood sugar, insulin resistance and liver fat accumulation, without affecting appetite or muscle mass;
2. Muscle gain:
Increase muscle mass (increase by 8%) and strength (increase by 40%) in elderly animals, reduce fat and inhibit chronic inflammation, and fight against muscle-reducing obesity;
3. Anti-inflammatory:
Reduce the risk of sepsis-induced acute kidney injury (AKI), and reduce systemic inflammatory response by inhibiting mitochondrial ROS generation and mtDNA release.

About BAM15
BAM15 is a new type of mitochondrial proton carrier uncoupler that significantly increases energy consumption and promotes fat oxidation without affecting muscle or appetite by destroying the proton gradient of the mitochondrial inner membrane. Preclinical studies have shown that it can effectively reverse obesity, improve insulin sensitivity, and reduce liver lipid accumulation and inflammation.
BAM 15 can be used to evaluate the oxidative phosphorylation and uncoupling state of cells to better understand the energy metabolism mechanism of cells. In addition, BAM 15 can also be used to study disease models such as obesity, diabetes, and neurodegenerative diseases to explore the relationship between these diseases and mitochondrial function and energy metabolism.