β-sitosterol

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[ Other Name ] Beta-Sitosterol; β-sitosterol
[ CAS No. ] 83-46-5
[ Molecular Formula ] C29H50O
[ Molecular Weight ] 414.71
[ Appearance ] White Fine Powder

[ Function ]
1. Cholesterol Reduction:
β-sitosterol effectively lowers blood cholesterol levels, thereby reducing the risk of cardiovascular disease.
2. Anti-inflammatory Effects:
β-sitosterol exhibits significant anti-inflammatory activity; it inhibits the production of pro-inflammatory cytokines and attenuates inflammatory responses.
3. Immune Modulation:
β-sitosterol modulates the immune system and enhances the body's immune response, demonstrating significant immunomodulatory effects.
4. Biocompatibility:
β-sitosterol possesses excellent biocompatibility, making it suitable for use in a wide range of cell-based and animal models.
5. Lipid Regulation and Cardiovascular Health:
β-sitosterol has demonstrated significant efficacy in cardiovascular research; by lowering cholesterol levels, it reduces the risk of atherosclerosis and cardiovascular disease.
6. Anti-inflammation:
β-sitosterol exhibits potent anti-inflammatory effects in models of inflammatory diseases, significantly attenuating inflammatory responses and protecting tissues from damage.

About β-sitosterol
β-Sitosterol is widely found in various plant oils, nuts and other plant seeds in nature, and also in some botanical medicines. β-Sitosterol is used in pharmaceutical raw materials and health food.
Beta-sitosterol possesses antioxidant properties, helping to defend against damage caused by free radicals. Free radicals are one of the primary causes of numerous diseases and the aging process. By inhibiting the generation of free radicals and scavenging those already present, beta-sitosterol protects cells from the detrimental effects of oxidative stress.
β-Sitosterol also exhibits anti-inflammatory effects. Inflammation is a common characteristic shared by many diseases, including arthritis, heart disease, and cancer. Beta-sitosterol can suppress inflammatory responses, thereby alleviating symptoms and tissue damage associated with inflammation. It exerts this effect by interfering with inflammatory signaling pathways and inhibiting the release of inflammatory mediators.
Furthermore, β-Sitosterol plays a role in lowering cholesterol levels and promoting cardiovascular health. It competes with dietary cholesterol for binding sites within the intestinal tract, thereby reducing cholesterol absorption. This mechanism helps to lower blood cholesterol levels and mitigate the risk of atherosclerosis.
In addition to the aforementioned effects, beta-sitosterol demonstrates a diverse range of pharmacological activities, including anti-cancer, immunomodulatory, antibacterial, and antiviral properties. It has shown potential anti-tumor efficacy in cancer therapy and is the subject of extensive research regarding its utility in the prevention and treatment of various forms of cancer.
β-Sitosterol is a naturally occurring compound endowed with a wide spectrum of physiological and pharmacological activities. Its antioxidant, anti-inflammatory, cholesterol-lowering, and cardioprotective properties establish it as a valuable ingredient in both pharmaceutical products and dietary supplements.