Apigenin

Apigenin

[ Synonyms ] 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;Versulin
[ CAS NO. ] 520-36-5 
[ Appearance ] Light-Yellow crystalline powder
[ Test Method ] HPLC
[ Plant Part Used ] Flower
[ Melting point ]  >300 °C(lit.)
[ Boiling point ]  333.35°C
[ Density ] 1.2319
[ Uses ] Antispasmodic, Antineoplastic, Topoisomerase I inhibitor
COA of Apigenin
[ Items ]
Assay(HPLC)Apigenin: 98%
Loss on drying:  ≤5%
Heavy Metal: <10ppm
Lead: <2ppm 
Arsenic: <2ppm 
Residual Solvents: Eur.Pharm 
[ Microbiological Items ]
Total Plate Count:<1000cfu/g
Yeast & Mold: <100cfu/g
Function of Apigenin
1.Anti-inflammatory effect
2.Lowering blood fat
3.Antioxidant effects
4.Bacteriostatic effect
5.Reduce the risk of cancer
6.Anti-hypertensive effects
About Apigenin
Apigenin is a polyphenol, and is one of the flavonoids found in many of the foods consumed by humans. It is widely distributed in warm tropical vegetables and fruits, especially in celery.It is a flavone with three OH groups on it. This compound is being widely studied for its anti-cancer properties. In particular, it has some anti-tumor properties that some other flavonoids lack.
Apigenin has potential to reduce the risk of cancer since it has anti-tumor activity.It can induce the apoptosis of human gastric cancer cells via activating mitochondrial signal transdution pathway and promotes proliferative inhibition and apoptotic induction of human acute myeloid leukaemia HL-60 cells by cisplatin(DDP).
Apigenin, as a non-toxic plant flavonoid,has been shown to free radical scavenging properties and antioxidant effects.
[ Storage ] Stored in dry and cool place, keep away from strong light and heat.
[ Shelf Life ] Two years when stored properly

 

 

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