Palbociclib(PD-0332991)
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[ Synonyms ] PD-0332991
[ CAS NO. ] 571190-30-2
[ Molecular Formula ] C24H29N7O2
[ Molecular Weight ] 447.53
[ Purity ] >99%
[ Appearance ] Yellow solid
About Palbociclib
Palbociclib is a CDK4/6 inhibitor used to treat hormone receptor-positive, HER2-negative advanced or metastatic breast cancer.
Palbociclib inhibits tumor growth by selectively inhibiting CDK4/6 protein kinases, preventing cancer cells from progressing from the G1 phase to the S phase of the cell cycle. It is primarily used to treat advanced or metastatic breast cancer that is hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-).
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