Oligopeptide-68 Acetate

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[ CAS NO. ] 1206525-47-4
[ Molecular Formula ] C62H91N17O21
[ Molecular Weight ] 1410.5
[ Appearance ] White Powder
[ Purity ] ≥95%

[ Function ]
1. Inhibits the activity of melanocyte-stimulating hormone (MSH), thereby reducing melanin formation and preventing the overproduction of melanin.
2. Mimics the binding of TGF-β to its receptor to achieve skin-brightening and whitening effects.
3. Reduces the levels of molecules associated with melanogenesis—such as MITF, TRP-1, TRP-2, and tyrosinase—thereby inhibiting tyrosinase activity and melanin synthesis.

[ Application ]
Oligopeptide-68 Acetate can be used in brightening creams, brightening foundations, pressed powders, and spot-correcting creams (for sunspots and freckles); it is typically added during the final stage of cosmetic production.

About Oligopeptide-68 Acetate
Oligopeptide-68 Acetate is a peptide and a novel skin-brightening ingredient. It functions by mimicking TGF-β to bind with cell-surface receptors and inhibiting the MITF pathway, thereby reducing both induced and constitutive pigmentation to achieve a skin-brightening effect. As a skin-brightening peptide, it employs a unique mechanism of action to both brighten the overall complexion and fade pigmentation caused by sun exposure.
Oligopeptide-68 Acetate inhibits melanocyte-stimulating hormone (MSH) and reduces melanin production, thereby preventing the overproduction of melanin. Its unique mechanism involves mimicking TGF-β to bind with cell-surface receptors and inhibiting the MITF pathway; this reduces both induced and constitutive pigmentation, resulting in a skin-brightening effect. It decreases the levels of key melanogenesis-related molecules—such as MITF, TRP-1, TRP-2, and tyrosinase—thereby inhibiting tyrosinase activity and melanin synthesis.
As a whitening peptide, Oligopeptide-68 Acetate demonstrates significant skin-brightening and whitening effects by inhibiting the formation and distribution of melanin. Its unique mechanism of action and high efficacy offer broad application prospects in the cosmetics industry.