Nicotinamide

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[ Other Name ] Niacinamide; Vitamin B3; Vitamin PP
[ CAS No. ] 98-92-0
[ Molecular Formula ] C6H6N2O
[ Molecular Weight ] 122.127
[ Appearance ] White Fine Powder
[ Purity ] 98%

[ Function ]
Skincare:
1. Whitening and Spot Fading:
Improves dullness and dark spots by blocking the transfer of melanosomes to keratinocytes.
2. Oil Control and Acne Treatment:
Inhibits the synthesis of triglycerides in sebaceous glands and reduces the proliferation of *Cutibacterium acnes*; effective for mild to moderate acne.
3. Barrier Repair:
Promotes the synthesis of ceramides, enhances the water-retention capacity of the stratum corneum, and alleviates dryness and sensitivity.
4. Anti-Photoaging:
Reduces UV-induced activity of matrix metalloproteinases (MMPs), helping to improve wrinkles and loss of skin elasticity.

Medicine:
1. Prevention and Treatment of Pellagra:
Corrects the triad of dermatitis, diarrhea, and dementia caused by niacin deficiency.
2. Skin Cancer Prevention:
Can reduce the incidence of non-melanoma skin cancer (NMSC) in high-risk populations.
3. Cardiovascular Disease:
Used as an adjunct therapy for conditions such as sick sinus syndrome and atrioventricular (AV) block.

About Nicotinamide
Nicotinamide, also known as Niacinamide or Vitamin B3, is a water-soluble form of vitamin B3 that plays an important role in cellular energy metabolism and the maintenance of normal physiological functions. It is widely used in dietary supplements, food fortification, pharmaceutical formulations, and cosmetic products.
Nicotinamide is also a popular skincare ingredient because of its role in supporting the skin barrier, improving the appearance of uneven skin tone, and maintaining healthy-looking skin.
Nicotinamide is used in cosmetics as a skin- and hair-conditioning ingredient, as well as in vitamin preparations and food enrichment.

Frequently Asked Questions
Q1: What is Nicotinamide used for?
It is used in skincare products, dietary supplements, food fortification, pharmaceutical preparations, and animal nutrition.

Q2: Is Nicotinamide the same as Niacinamide?
Yes. Nicotinamide and niacinamide are two names for the same chemical compound.

Q3: Is Nicotinamide good for skin?
Topical niacinamide is widely used to support the skin barrier, improve hydration, and enhance the appearance of uneven skin tone. Results depend on concentration, formulation, and consistent use.

Q5: Can Nicotinamide be used in supplements and cosmetics?
Yes, but the ingredient must meet the appropriate quality, purity, safety, and regulatory requirements for its intended application.