Glucosylrutin

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[ Other Name ] α-Glucosylrutin; Rutin Glucoside
[ CAS NO. ] 130603-71-3
[ Molecular Formula ] C33H40O21
[ Molecular Weight ] 772.66
[ Appearance ] Light Yellow to Yellow Powder
[ Purity ] 99%

[ Function ]
1. Scavenges free radicals, inhibits lipid peroxidation, and protects cells from oxidative stress damage (e.g., caused by H₂O₂);
2. Inhibits UVA-induced expression of MMP-1 and MMP-2, slows collagen degradation, and combats photoaging;
3. Reduces UV-induced skin erythema and pigmentation;
4. Enhances antioxidant effects and promotes skin barrier repair when used in combination with ingredients such as Vitamin C;
5. Inhibits UV-induced erythema and reduces wrinkles;
6. Protects collagen and inhibits the production of collagen-degrading enzymes;
7. Prevents pigment fading;
8. Prevents fragrance degradation;
9. Inhibits lipid peroxidation;

[ Application ]
Skincare products: Used in anti-aging and sun protection formulations to reduce damage caused by photoaging.

About Glucosylrutin
Glucosylrutin is a semi-synthetic flavonoid derivative created by attaching a glucose molecule to rutin (a natural plant pigment also known as vitamin P). This modification is done to greatly improve rutin's water solubility and stability, making it more useful for various applications. Its main attraction is its strong antioxidant power and ability to protect the skin from UV damage.
As a powerful antioxidant, it neutralizes harmful free radicals that cause skin aging and damage. Its ability to absorb UV radiation makes it a valuable ingredient in sunscreens and anti-aging creams, where it often works synergistically with other UV filters. One study showed that a sunscreen formulation with glucosylrutin achieved an SPF of 33.83, a significant increase over using UV filters alone. It has also shown clinical effectiveness in preventing skin conditions related to UV exposure, like polymorphous light eruption (PLE).
Glucosylrutin offers benefits such as UV and blue light protection, free radical scavenging, antioxidant activity, prevention of discoloration in raw Vitamin C powder, and color preservation for natural pigments.
Glucosylrutin is used in cosmetics and other fields; it offers excellent antioxidant properties and UV-absorbing capabilities, helping to protect against photoaging, delay the aging process, and provide defense against blue light.