Piperine

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[ Herb Source ] Piper nigrum L.
[ CAS NO. ] 94–62–2
[ Molecular Formula ] C17H19NO3
[ Molecular Weight ] 285.343
[ Appearance ] Light Yellow to White Fine Powder
[ Purity ] ≥98% (HPLC)

[ Function ]
1. It can improve the absorption rate of various nutrients or drugs by inhibiting metabolic enzymes in the intestines (such as CYP3A4) and activating transport proteins (such as P-glycoprotein);
2. It can scavenge free radicals and reduce oxidative stress damage to cells;
3. It can lower lipid peroxidation levels and protect organs such as the liver and heart;
4. It can assist in regulating blood sugar by increasing insulin sensitivity;
5. It improves lipid metabolism and reduces fat accumulation;
6. It can reduce β-amyloid protein deposition and improve memory function;
7. It has a certain inhibitory effect on pathogenic bacteria such as Staphylococcus aureus and Escherichia coli;

About Piperine
Piperine is the alkaloid responsible for the pungency of black pepper and long pepper, along with chavicine (an isomer of piperine).Piperine has analgesic, anti-inflammatory, appetite-stimulating, digestive, and diuretic effects and functions.
Piperine is often added to prepared food to enhance aroma and flavor.It can Promote drug absorption, and improve the effectiveness of the drug function. In clinical practice, it can induce calm (sedative effect) or to induce sleep (hypnotic effect), and used to make anticonvulsant, antidepressant, and muscle relaxation drug.
Piperine has also been found to inhibit human CYP3A4 and P-glycoprotein, enzymes important for the metabolism and transport of xenobiotics and metabolites.In animal studies, piperine also inhibited other enzymes important in drug metabolism.By inhibiting drug metabolism, piperine may increase the bioavailability of various compounds.

[ Storage ] Stored in dry and cool place, keep away from strong light and heat.
[ Shelf Life ] Two years when stored properly.