Indirubin (Couraupitine B)

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[ Other Name ] Indigo Red; Couroupitine B
[ Herb Source ] Indigofera tinctoria L
[ Specification ] 98%Indirubin
[ Detection Method ] HPLC
[ CAS NO. ] 906748-38-7
[ Molecular Formula ] C16H10N2O2
[ Molecular Weight ] 262.268

[ Function ]
1. Anti-tumor effects;
2. Inhibits the release of inflammatory factors (such as TNF-α and IL-6), alleviating inflammatory responses;
3. Regulates immune cell function;
4. Antiviral and antibacterial;
5. Reduces the damage of chemotherapy drugs to normal hematopoietic stem cells, improving patients' blood counts;

About Indirubin
Indirubin is the purple component of blue indigo dye, extracted from plants such as Polygonum tinctorium, Isatis indigotica, and Isatis tinctoria.Chemically, indirubin is a 3,2'-bisindole, a stable isomer of indigo. It has been shown to inhibit cell growth and induce apoptosis and differentiation of leukemic cells (1-8).
The main effects of indirubin include anti-tumor, anti-inflammatory, and immunomodulatory effects. It is widely used in the adjuvant treatment of chronic myeloid leukemia (CML) and can work by inhibiting abnormal cell proliferation.