Osteogenic Growth Peptide

Buy Osteogenic Growth Peptide (OGP) at Wholesale Price. High Quality. Low Price. Inquiry Now!
Osteogenic Growth Peptide Price & Cost; Get Osteogenic Growth Peptide For Sale From Manufacturer/Supplier, Benefits - Bolise.

[ Other Name ] OGP
[ Sequence ] Ala-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly
[ CAS NO. ] 132996-61-3
[ Molecular Formula ] C68H110N22O18
[ Molecular Weight ]1523.74
[ Appearance ] White Powder
[ Purity ] 99%

[ Function ]
1. It can increase bone formation in the body, increase the density of trabecular bone, and promote fracture healing;
2. Its function in vitro is to promote the mitogen and alkaline phosphatase activities of bone marrow stromal cells and promote matrix mineralization;
3. Polypeptide growth factors that promote bone formation and stimulate hematopoiesis;

About Osteogenic Growth Peptide
Osteogenic Growth Peptide is a type of protein that promotes the formation and repair of bone tissue.
Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C-terminus of histone H4, whose sequence contains a highly conserved 14-amino acid motif (NH 2 -ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells.
Osteogenic growth peptide is a signaling protein that transmits messages between cells to promote the formation and reconstruction of bone tissue. It participates in regulating the proliferation, differentiation and function of bone cells and has important biological activity.
Osteogenic growth peptides are often used to promote the repair of bone defects and fractures. It can be used in orthopedic surgery for bone fusion, nonunion and bone graft replacement treatments, and is also suitable for use in dentistry. In addition, osteogenic growth peptides are also used in laboratory research and development of new bone tissue engineering materials.
At present, the main preparation method is to obtain purified osteogenic growth peptide through genetic engineering technology. This method can introduce human genes into eukaryotic cells through transgenic technology, and then allow the eukaryotic cells to express and secrete osteogenic growth peptides. Next, it is necessary to go through complex purification processes, such as centrifugation, infiltration, chromatography, etc., to obtain high-purity osteogenic growth peptides.