Naproxen Sodium

Naproxen Sodium

[ Chemical Name ] (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt
[ CAS NO. ] 26159-34-2 
[ Molecular Formula ] C14H13NaO3
[ Molecular weight ] 252.245
[ Appearance ] White or white crystalline powder
[ Melting point ]  250-251°C
[ Solubility ] Freely soluble in water, freely soluble or soluble in methanol, sparingly soluble in ethanol (96 per cent).
[ Uses ]  Used as anti-inflammatory analgesic
COA of Naproxen Sodium
A.Infrared absorption: Meet the standard
B.UV ray absorbtion: At 272nm wavelength, the same method as the standard detection, absorption coefficient deviation of not more than 3%.
Loss on drying: 0.06%
Specific rotation: -16.7°
Heavy metal:  ≤0.002% 
Free naproxen:  0.07% 
Residual solvent - acetone: <0.06%
Chromatographic purity: Meet the standard
Assay: 99.7%  
About Naproxen Sodium
Naproxen Sodium's medical uses are related to its mechanism of action as an anti-inflammatory compound. Naproxen Sodium is used to treat a variety of inflammatory conditions and symptoms that are due to excessive inflammation, such as pain and fever (Naproxen Sodium has fever-reducing, or antipyretic, properties in addition to its anti-inflammatory activity). Notably, not all medications that reduce fever are anti-inflammatory compounds (such as paracetamol). Inflammatory sources of pain that may respond to Naproxen Sodium's anti-inflammatory activity are conditions such as migraine, osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, and bursitis.
Because of its anti-inflammatory mechanism of action, one would not expect Naproxen Sodium to be useful in treating non-inflammatory causes of pain (e.g., diabetic nerve pain).
Naproxen sodium is used as a "bridge therapy" in medication-overuse headache to slowly take patients off of other medications.

 

 

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